Cross-recognition of a pit viper (Crotalinae) polyspecific antivenom explored through high-density peptide microarray epitope mapping.

• المؤلفون الرئيسيون: Mikael Engmark (مؤلف), Bruno Lomonte (مؤلف), José María Gutiérrez (مؤلف), Andreas H Laustsen (مؤلف), Federico De Masi (مؤلف), Mikael R Andersen (مؤلف), Ole Lund (مؤلف)
• التنسيق: كتاب
• منشور في: Public Library of Science (PLoS), 2017-07-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Snakebite antivenom is a 120 years old invention based on polyclonal mixtures of antibodies purified from the blood of hyper-immunized animals. Knowledge on antibody recognition sites (epitopes) on snake venom proteins is limited, but may be used to provide molecular level explanations for antivenom...