PGE2 Desensitizes β-Agonist Effect on Human Lung Fibroblast-Mediated Collagen Gel Contraction through Upregulating PDE4

In the current study, we investigated the effect of a long-acting β-agonist (salmeterol) and a phosphodiesterase 4 (PDE4) inhibitor (cilomilast) on human lung fibroblast-mediated collagen gel contraction. Higher concentrations of salmeterol (10−7 and 10−6 M) inhibited fibroblast-mediated collagen ge...

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Main Authors: Qiuhong Fang (Author), Yingmin Ma (Author), Jing Wang (Author), Joel Michalski (Author), Stephen I. Rennard (Author), Xiangde Liu (Author)
Format: Book
Published: Hindawi Limited, 2013-01-01T00:00:00Z.
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3rd Floor Main Library

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