Dehydroflavonolignans from Silymarin Potentiate Transition Metal Toxicity In Vitro but Are Protective for Isolated Erythrocytes Ex Vivo

Dehydroflavonolignans from Silymarin Potentiate Transition Metal Toxicity In Vitro but Are Protective for Isolated Erythrocytes Ex Vivo

2,3-Dehydrosilybin (DHS) was previously shown to chelate and reduce both copper and iron ions. In this study, similar experiments with 2,3-dehydrosilychristin (DHSCH) showed that this congener of DHS also chelates and reduces both metals. Statistical analysis pointed to some differences between both...

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Main Authors: Zuzana Lomozová (Author), Václav Tvrdý (Author), Marcel Hrubša (Author), Maria Carmen Catapano (Author), Kateřina Macáková (Author), David Biedermann (Author), Radim Kučera (Author), Vladimír Křen (Author), Přemysl Mladěnka (Author), Kateřina Valentová (Author)
Format: Book
Published: MDPI AG, 2021-04-01T00:00:00Z.
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3rd Floor Main Library

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