QSAR-Driven Design and Discovery of Novel Compounds With Antiplasmodial and Transmission Blocking Activities

• Main Authors: Marilia N. N. Lima (Author), Cleber C. Melo-Filho (Author), Gustavo C. Cassiano (Author), Bruno J. Neves (Author), Vinicius M. Alves (Author), Rodolpho C. Braga (Author), Pedro V. L. Cravo (Author), Eugene N. Muratov (Author), Juliana Calit (Author), Daniel Y. Bargieri (Author), Fabio T. M. Costa (Author), Carolina H. Andrade (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Malaria is a life-threatening infectious disease caused by parasites of the genus Plasmodium, affecting more than 200 million people worldwide every year and leading to about a half million deaths. Malaria parasites of humans have evolved resistance to all current antimalarial drugs, urging for the...