Involvement of cyclic guanosine monophosphate-dependent protein kinase I in renal antifibrotic effects of serelaxin

• 主要な著者: Veronika Wetzl (著者), Elisabeth Schinner (著者), Frieder Kees (著者), Franz Hofmann (著者), Lothar Faerber (著者), Jens Schlossmann (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2016-07-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Introduction: Kidney fibrosis has shown to be ameliorated through the involvement of cyclic guanosine monophosphate (cGMP) and its dependent protein kinase I (cGKI). Serelaxin, the recombinant form of human relaxin-II, increases cGMP levels and has shown beneficial effects on kidney function in acut...