Patients with Systemic Lupus Erythematosus Show Increased Levels and Defective Function of CD69+ T Regulatory Cells

• Main Authors: Marlen Vitales-Noyola (Author), Brenda Oceguera-Maldonado (Author), Perla Niño-Moreno (Author), Nubia Baltazar-Benítez (Author), Lourdes Baranda (Author), Esther Layseca-Espinosa (Author), Carlos Abud-Mendoza (Author), Roberto González-Amaro (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

T regulatory (Treg) cells have a key role in the pathogenesis of chronic inflammatory and autoimmune diseases. A CD4+CD69+ T cell subset has been described that behaves as Treg lymphocytes, exerting an important immune suppressive effect. In this study, we analyzed the levels and function of CD4+CD6...