Validation of warfarin enantiomer analysis method in plasma using high-performance liquid chromatography fluorescence detector

• Main Authors: Norisca Aliza Putriana (Author), Taofik Rusdiana (Author), Tina Rostinawati (Author), Mohammad Rizki Akbar (Author), Febrina Amelia Saputri (Author), Siti Utami (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Warfarin (WF) is an anticoagulant commonly used for thromboembolism-related diseases.This study aims to assess the pharmacokinetic profile of WF. The stereospecific interaction of S-and R-WF requires quantification of the enantiomer to determine the pharmacokinetic profile. The analysis method of th...