Piperlongumine inhibits migration and proliferation of castration-resistant prostate cancer cells via triggering persistent DNA damage

• Main Authors: Ding-fang Zhang (Author), Zhi-chun Yang (Author), Jian-qiang Chen (Author), Xiang-xiang Jin (Author), Yin-da Qiu (Author), Xiao-jing Chen (Author), Hong-yi Shi (Author), Zhi-guo Liu (Author), Min-shan Wang (Author), Guang Liang (Author), Xiao-hui Zheng (Author)
• Format: Book
• Published: BMC, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Metastatic castration-resistant prostate cancer (CRPC) is the leading cause of death among men diagnosed with prostate cancer. Piperlongumine (PL) is a novel potential anticancer agent that has been demonstrated to exhibit anticancer efficacy against prostate cancer cells. Howeve...