Injected Human Muscle Precursor Cells Overexpressing PGC-1α Enhance Functional Muscle Regeneration after Trauma

• Main Authors: Deana Haralampieva (Author), Souzan Salemi (Author), Thomas Betzel (Author), Ivana Dinulovic (Author), Stefanie D. Krämer (Author), Roger Schibli (Author), Tullio Sulser (Author), Christoph Handschin (Author), Simon M. Ametamey (Author), Daniel Eberli (Author)
• Format: Book
• Published: Hindawi Limited, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

While many groups demonstrated new muscle tissue formation after muscle precursor cell (MPC) injection, the capacity of these cells to heal muscle damage, for example, sphincter in stress urinary incontinence, in long-term is still limited. Therefore, the first goal of our project was to optimize th...