Genipin Inhibits RANKL-Induced Osteoclast Differentiation Through Proteasome-Mediated Degradation of c-Fos Protein and Suppression of NF-κB Activation

• Main Authors: Chang Hoon Lee (Author), Sung-Chul Kwak (Author), Ju-Young Kim (Author), Hyun Mee Oh (Author), Mun Chual Rho (Author), Kwon-Ha Yoon (Author), Wan-Hee Yoo (Author), Myeung Su Lee (Author), Jaemin Oh (Author)
• Format: Book
• Published: Elsevier, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

People over the age of 50 are at risk of osteoporotic fracture, which may lead to increased morbidity and mortality. Osteoclasts are responsible for bone resorption in bone-related disorders. Genipin is a well-known geniposide aglycon derived from Gardenia jasminoides, which has long been used in or...