SILAC-based quantitative proteomics using mass spectrometry quantifies endoplasmic reticulum stress in whole HeLa cells

The unfolded protein response (UPR) involves extensive proteome remodeling in many cellular compartments. To date, a comprehensive analysis of the UPR has not been possible because of technological limitations. Here, we employ stable isotope labeling with amino acids in cell culture (SILAC)-based pr...

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Main Authors: Daniel N. Itzhak (Author), Francesca Sacco (Author), Nagarjuna Nagaraj (Author), Stefka Tyanova (Author), Matthias Mann (Author), Marta Murgia (Author)
Format: Book
Published: The Company of Biologists, 2019-11-01T00:00:00Z.
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