Study of penetration mechanism of labrasol on rabbit cornea by Ussing chamber, RT-PCR assay, Western blot and immunohistochemistry

• Main Authors: Pan Guo (Author), Nan Li (Author), Lili Fan (Author), Jun Lu (Author), Boying Liu (Author), Bing Zhang (Author), Yumei Wu (Author), Zhidong Liu (Author), Jiawei Li (Author), Jiaxin Pi (Author), Dongli Qi (Author)
• Format: Book
• Published: Elsevier, 2019-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Labrasol, as a non-ionic surfactant, can enhance the permeation and absorption of drugs, and is extensively used in topical, transdermal, and oral pharmaceutical preparations as an emulsifier and absorption enhancer. Recent studies in our laboratory have indicated that labrasol has a strong absorpti...