Quality control recommendations for RNASeq using FFPE samples based on pre-sequencing lab metrics and post-sequencing bioinformatics metrics

• Үндсэн зохиолчид: Yuanhang Liu (Зохиогч), Aditya Bhagwate (Зохиогч), Stacey J. Winham (Зохиогч), Melissa T. Stephens (Зохиогч), Brent W. Harker (Зохиогч), Samantha J. McDonough (Зохиогч), Melody L. Stallings-Mann (Зохиогч), Ethan P. Heinzen (Зохиогч), Robert A. Vierkant (Зохиогч), Tanya L. Hoskin (Зохиогч), Marlene H. Frost (Зохиогч), Jodi M. Carter (Зохиогч), Michael E. Pfrender (Зохиогч), Laurie Littlepage (Зохиогч), Derek C. Radisky (Зохиогч), Julie M. Cunningham (Зохиогч), Amy C. Degnim (Зохиогч), Chen Wang (Зохиогч)
• Формат: Ном
• Хэвлэсэн: BMC, 2022-09-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Abstract Background Formalin-fixed, paraffin-embedded (FFPE) tissues have many advantages for identification of risk biomarkers, including wide availability and potential for extended follow-up endpoints. However, RNA derived from archival FFPE samples has limited quality. Here we identified paramet...