Inhibition of autoimmune Chagas-like heart disease by bone marrow transplantation.

• Main Authors: Maria C Guimaro (Author), Rozeneide M Alves (Author), Ester Rose (Author), Alessandro O Sousa (Author), Ana de Cássia Rosa (Author), Mariana M Hecht (Author), Marcelo V Sousa (Author), Rafael R Andrade (Author), Tamires Vital (Author), Jiří Plachy (Author), Nadjar Nitz (Author), Jiří Hejnar (Author), Clever C Gomes (Author), Antonio R L Teixeira (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Infection with the protozoan Trypanosoma cruzi manifests in mammals as Chagas heart disease. The treatment available for chagasic cardiomyopathy is unsatisfactory. METHODS/PRINCIPAL FINDINGS:To study the disease pathology and its inhibition, we employed a syngeneic chicken model refractor...