Primary T‐cell‐based delivery platform for in vivo synthesis of engineered proteins

• Autori principali: Harikrishnan Radhakrishnan (Autore), Sherri L. Newmyer (Autore), Marvin A. Ssemadaali (Autore), Harold S. Javitz (Autore), Parijat Bhatnagar (Autore)
• Natura: Libro
• Pubblicazione: Wiley, 2024-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Abstract Primary T cell has been transformed into a cell‐based delivery platform that synthesizes complex biologics at the disease site with spatiotemporal resolution. This broadly applicable technology can circumvent toxicities due to systemic administration of biologics that necessitates the use o...