Gentamicin Population Pharmacokinetics in Pediatric Patients-A Prospective Study with Data Analysis Using the saemix Package in R

• Main Authors: Paolo Paioni (Author), Vera F. Jäggi (Author), Romy Tilen (Author), Michelle Seiler (Author), Philipp Baumann (Author), Dominic S. Bräm (Author), Carole Jetzer (Author), Robin T. U. Haid (Author), Aljoscha N. Goetschi (Author), Roland Goers (Author), Daniel Müller (Author), Diana Coman Schmid (Author), Henriette E. Meyer zu Schwabedissen (Author), Bernd Rinn (Author), Christoph Berger (Author), Stefanie D. Krämer (Author)
• Format: Book
• Published: MDPI AG, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aminoglycoside gentamicin is used for the empirical treatment of pediatric infections. It has a narrow therapeutic window. In this prospective study at University Children's Hospital Zurich, Switzerland, we aimed to characterize the pharmacokinetics of gentamicin in pediatric patients and p...