The absence of dystrophin brain isoform expression in healthy human heart ventricles explains the pathogenesis of 5' X-linked dilated cardiomyopathy

• Egile Nagusiak: Neri Marcella (Egilea), Valli Emanuele (Egilea), Alfano Giovanna (Egilea), Bovolenta Matteo (Egilea), Spitali Pietro (Egilea), Rapezzi Claudio (Egilea), Muntoni Francesco (Egilea), Banfi Sandro (Egilea), Perini Giovanni (Egilea), Gualandi Francesca (Egilea), Ferlini Alessandra (Egilea)
• Formatua: Liburua
• Argitaratua: BMC, 2012-03-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>In X-linked dilated cardiomyopathy due to <it>dystrophin </it>mutations which abolish the expression of the M isoform (5'-XLDC), the skeletal muscle is spared through the up-regulation of the Brain (B) isoform, a com...