Serological and PCR-based markers of ocular Chlamydia trachomatis transmission in northern Ghana after elimination of trachoma as a public health problem.

• Main Authors: Laura G Senyonjo (Author), Oscar Debrah (Author), Diana L Martin (Author), Adwoa Asante-Poku (Author), Stephanie J Migchelsen (Author), Sarah Gwyn (Author), Dzeidzom K deSouza (Author), Anthony W Solomon (Author), David Agyemang (Author), Nana Biritwum-Kwadwo (Author), Benjamin Marfo (Author), Didier Bakajika (Author), Ernest O Mensah (Author), Agatha Aboe (Author), Joseph Koroma (Author), James Addy (Author), Robin Bailey (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2018-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Validation of elimination of trachoma as a public health problem is based on clinical indicators, using the WHO simplified grading system. Chlamydia trachomatis (Ct) infection and anti-Ct antibody responses (anti-Pgp3) have both been evaluated as alternative indicators in settings with va...