Cytokines TNF-α, IL-6, IL-17F, and IL-4 Differentially Affect Osteogenic Differentiation of Human Adipose Stem Cells

• Principais autores: Angela P. Bastidas-Coral (Autor), Astrid D. Bakker (Autor), Behrouz Zandieh-Doulabi (Autor), Cornelis J. Kleverlaan (Autor), Nathalie Bravenboer (Autor), Tim Forouzanfar (Autor), Jenneke Klein-Nulend (Autor)
• Formato: Livro
• Publicado em: Hindawi Limited, 2016-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

During the initial stages of bone repair, proinflammatory cytokines are released within the injury site, quickly followed by a shift to anti-inflammatory cytokines. The effect of pro- and anti-inflammatory cytokines on osteogenic differentiation of mesenchymal stem cells is controversial. Here, we i...