Interleukin-6 via Toll-Like Receptor 3 Signaling Attenuates the Expression of Proinflammatory Chemokines in Human Podocytes

• Main Authors: Hidenori Umetsu (Author), Shojiro Watanabe (Author), Tadaatsu Imaizumi (Author), Tomomi Aizawa (Author), Koji Tsugawa (Author), Shogo Kawaguchi (Author), Kazuhiko Seya (Author), Tomoh Matsumiya (Author), Hiroshi Tanaka (Author)
• Formato: Libro
• Publicado: Karger Publishers, 2021-04-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Background: Although toll-like receptor 3 (TLR3) signaling is involved in the development of certain chronic kidney diseases, the specific molecular mechanisms underlying inflammatory reactions via activation of TLR3 signaling in human podocytes remain unclear. Interleukin (IL)-6 is a pleiotropic cy...