APEX1 regulates alternative splicing of key tumorigenesis genes in non-small-cell lung cancer

• Main Authors: Li Peng (Author), Yuwei Liu (Author), Jing Chen (Author), Mengxin Cheng (Author), Ying Wu (Author), Min Chen (Author), Ya Zhong (Author), Dan Shen (Author), Ling Chen (Author), Xujun Ye (Author)
• Format: Book
• Published: BMC, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Aberrant alternative splicing (AS) contributes to tumor progression. Previous studies have shown that apurinic-apyrimidinic endonuclease-1 (APEX1) is involved in tumor progression. It is unknown whether APEX1 functions in tumor progression by regulation of AS. It is also unknown...