Co-encapsulation of docetaxel and cyclosporin A into SNEDDS to promote oral cancer chemotherapy

• Main Authors: Weiping Cui (Author), Hanqing Zhao (Author), Chen Wang (Author), Yao Chen (Author), Cong Luo (Author), Shenwu Zhang (Author), Bingjun Sun (Author), Zhonggui He (Author)
• Format: Book
• Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Self-nanoemulsifying drug delivery system (SNEDDS) have been considered as a promising platform for oral delivery of many BCS (biopharmaceutics classification system) class IV drugs, such as docetaxel (DTX). However, oral chemotherapy with DTX is also restricted by its active P-glycoprotein (P-gp) e...