The regulator of G-protein signaling RGS16 promotes insulin secretion and β-cell proliferation in rodent and human islets

• Hoofdauteurs: Kevin Vivot (Auteur), Valentine S. Moullé (Auteur), Bader Zarrouki (Auteur), Caroline Tremblay (Auteur), Arturo D. Mancini (Auteur), Hasna Maachi (Auteur), Julien Ghislain (Auteur), Vincent Poitout (Auteur)
• Formaat: Boek
• Gepubliceerd in: Elsevier, 2016-10-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Objective: G protein-coupled receptor (GPCR) signaling regulates insulin secretion and pancreatic β cell-proliferation. While much knowledge has been gained regarding how GPCRs are activated in β cells, less is known about the mechanisms controlling their deactivation. In many cell types, terminatio...