Genetic profiling of primary and secondary tumors from patients with lung adenocarcinoma and bone metastases reveals targeted therapy options

• Main Authors: Long Huang (Author), Xiao-Liu Jiang (Author), Hong-Bin Liang (Author), Jian-Cheng Li (Author), Li-Han Chin (Author), Jian-Ping Wei (Author), Rui-Ru Wang (Author), Jing Cai (Author), Qiang Xiong (Author), Lien-Tu Wang (Author), David S. Cram (Author), An-Wen Liu (Author)
• Format: Book
• Published: BMC, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Patients newly diagnosed with lung adenocarcinoma with bone metastases (LABM) have poor survival rates after treatment with conventional therapies. To improve outcomes, we retrospectively investigated whether the application of a more comprehensive genetic test of tumor biopsies...