Genetic profiling of primary and secondary tumors from patients with lung adenocarcinoma and bone metastases reveals targeted therapy options

• Главные авторы: Long Huang (Автор), Xiao-Liu Jiang (Автор), Hong-Bin Liang (Автор), Jian-Cheng Li (Автор), Li-Han Chin (Автор), Jian-Ping Wei (Автор), Rui-Ru Wang (Автор), Jing Cai (Автор), Qiang Xiong (Автор), Lien-Tu Wang (Автор), David S. Cram (Автор), An-Wen Liu (Автор)
• Формат: ‌
• Опубликовано: BMC, 2020-09-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Abstract Background Patients newly diagnosed with lung adenocarcinoma with bone metastases (LABM) have poor survival rates after treatment with conventional therapies. To improve outcomes, we retrospectively investigated whether the application of a more comprehensive genetic test of tumor biopsies...