Development and application of a pediatric mechanistic kidney model

Abstract Pediatric physiologically‐based pharmacokinetic (P‐PBPK) models have been used to predict age related changes in the pharmacokinetics (PKs) of renally cleared drugs mainly in relation to changes in glomerular filtration rate. With emerging data on ontogeny of renal transporters, mechanistic...

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Bibliographic Details
Main Authors: Farzaneh Salem (Author), Ben G. Small (Author), Trevor N. Johnson (Author)
Format: Book
Published: Wiley, 2022-07-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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