Salmonella-mediated blood‒brain barrier penetration, tumor homing and tumor microenvironment regulation for enhanced chemo/bacterial glioma therapy

• Main Authors: Ze Mi (Author), Qing Yao (Author), Yan Qi (Author), Jinhai Zheng (Author), Jiahao Liu (Author), Zhenguo Liu (Author), Hongpei Tan (Author), Xiaoqian Ma (Author), Wenhu Zhou (Author), Pengfei Rong (Author)
• Format: Book
• Published: Elsevier, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chemotherapy is an important adjuvant treatment of glioma, while the efficacy is far from satisfactory, due not only to the biological barriers of blood‒brain barrier (BBB) and blood‒tumor barrier (BTB) but also to the intrinsic resistance of glioma cells via multiple survival mechanisms such as up-...