Pharmacodynamics and pharmacokinetics of a new type of recombinant insulin Lisargine injection

• Main Authors: Jiangjie Lu (Author), Yong Zeng (Author), Xiulin Yi (Author), Hongmei Zhang (Author), Lin Zhu (Author), Lixin Jiang (Author), Jing Li (Author), Wei Zhou (Author), Hong Zhu (Author), Aijun Xiong (Author)
• Format: Book
• Published: BMC, 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Recombinant insulin Lisargine is a new type of insulin. In this study, we aimed to compare its pharmacodynamic (PD) and pharmacokinetic (PK) with Lantus. Methods The PD test was performed by exploring the effect of single administration on blood glucose of normal rats and STZ-ind...