Incretin-like effects of small molecule trace amine-associated receptor 1 agonists

• Main Authors: Susanne Raab (Author), Haiyan Wang (Author), Sabine Uhles (Author), Nadine Cole (Author), Ruben Alvarez-Sanchez (Author), Basil Künnecke (Author), Christoph Ullmer (Author), Hugues Matile (Author), Marc Bedoucha (Author), Roger D. Norcross (Author), Nickki Ottaway-Parker (Author), Diego Perez-Tilve (Author), Karin Conde Knape (Author), Matthias H. Tschöp (Author), Marius C. Hoener (Author), Sabine Sewing (Author)
• Format: Book
• Published: Elsevier, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Type 2 diabetes and obesity are emerging pandemics in the 21st century creating worldwide urgency for the development of novel and safe therapies. We investigated trace amine-associated receptor 1 (TAAR1) as a novel target contributing to the control of glucose homeostasis and body weight...