Discovery of the anti-angiogenesis effect of eltrombopag in breast cancer through targeting of HuR protein
HuR (human antigen R), an mRNA-binding protein responsible for poor prognosis in nearly all kinds of malignancies, is a potential anti-tumor target for drug development. While screening HuR inhibitors with a fluorescence polarization (FP) based high-throughput screening (HTS) system, the clinically...
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Elsevier,
2020-08-01T00:00:00Z.
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