Towards a New Generation of Hormone Therapies: Design, Synthesis and Biological Evaluation of Novel 1,2,3-Triazoles as Estrogen-Positive Breast Cancer Therapeutics and Non-Steroidal Aromatase Inhibitors
Aromatase inhibitors (AIs) show promising features as drugs to treat estrogen-responsive breast cancer as they block aromatase activity, the key enzyme in estrogen synthesis. The current AIs approved by the Food and Drug Administration for breast cancer treatment present severe adverse effects. For...
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Main Authors: | Huda R. M. Rashdan (Author), Mohamad T. Abdelrahman (Author), Anna Chiara De Luca (Author), Maria Mangini (Author) |
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Format: | Book |
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MDPI AG,
2024-01-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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