N-acetyl-L-cysteine functionalized nanostructured lipid carrier for improving oral bioavailability of curcumin: preparation, in vitro and in vivo evaluations

• Main Authors: Cihui Tian (Author), Sajid Asghar (Author), Yifan Wu (Author), Daddy Kambere Amerigos (Author), Zhipeng Chen (Author), Mei Zhang (Author), Lining Yin (Author), Lin Huang (Author), Qineng Ping (Author), Yanyu Xiao (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The application of orally administered nanoparticles in the circulation system is limited by the secretion and shedding of intestinal tract mucous layer. In order to enhance mucoadhesion and mucus penetration of curcumin (Cur)-loaded nanostructured lipid carrier (NLC) after oral administration, a ne...