Cumingianoside A, a Phyto-Triterpenoid Saponin Inhibits Acquired BRAF Inhibitor Resistant Melanoma Growth via Programmed Cell Death

Mutated proto-oncogene BRAF is a bona fide therapeutic target for melanomas. Regrettably, melanoma acquires resistance to BRAF inhibitors, e.g., vemurafenib (PLX4032) casting doubt on this promising melanoma targeted therapy. In this study, we explored the bioactivity of triterpenoid saponin cumingi...

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Main Authors: Biljana Cvetanova (Author), Ya-Ching Shen (Author), Lie-Fen Shyur (Author)
Format: Book
Published: Frontiers Media S.A., 2019-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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