Characterization of an N-terminal Nav1.5 channel variant - a potential risk factor for arrhythmias and sudden death?

Characterization of an N-terminal Nav1.5 channel variant - a potential risk factor for arrhythmias and sudden death?

Abstract Background Alterations in the SCN5A gene encoding the cardiac sodium channel Nav1.5 have been linked to a number of arrhythmia syndromes and diseases including long-QT syndrome (LQTS), Brugada syndrome (BrS) and dilative cardiomyopathy (DCM), which may predispose to fatal arrhythmias and su...

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Main Authors: Stefanie Scheiper-Welling (Author), Paolo Zuccolini (Author), Oliver Rauh (Author), Britt-Maria Beckmann (Author), Christof Geisen (Author), Anna Moroni (Author), Gerhard Thiel (Author), Silke Kauferstein (Author)
Format: Book
Published: BMC, 2020-11-01T00:00:00Z.
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3rd Floor Main Library

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