Synthesis and Biological Characterization of a New Norbormide Derived Bodipy FL-Conjugated Fluorescent Probe for Cell Imaging

• Main Authors: Claudio D'Amore (Author), Genny Orso (Author), Alessia Forgiarini (Author), Giulio Ceolotto (Author), David Rennison (Author), Giovanni Ribaudo (Author), Morgan Jay-Smith (Author), Brian Hopkins (Author), Margaret A. Brimble (Author), Sergio Bova (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Norbormide (NRB) is a selective rat toxicant endowed with vasoconstrictor activity confined to the rat peripheral arteries. In a recent work we used a fluorescent derivative of NRB (NRB-AF12), obtained by coupling the NBD fluorophore to the parent molecule via a linker, in order to gain...