(Pro)renin receptor aggravates myocardial pyroptosis in diabetic cardiomyopathy through AMPK-NLRP3 pathway

• Autori principali: Shengnan Li (Autore), Jingjing Zhang (Autore), Yuewen Zhao (Autore), Li Kang (Autore), Haipeng Jie (Autore), Bo Dong (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2024-10-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

IntroductionAs one of the most common complications of diabetes, diabetic cardiomyopathy (DCM) is the main cause of heart failure in patients with diabetes. However, the lack of effective treatments for DCM remains a clinical challenge. (Pro) renin receptor (PRR) is a member of renin angiotensin ald...