WTAP mediates the anti-inflammatory effect of Astragalus mongholicus polysaccharide on THP-1 macrophages

• Main Authors: Haijiao Long (Author), Haiyue Lin (Author), Pan Zheng (Author), Lianjie Hou (Author), Ming Zhang (Author), Shuyun Lin (Author), Kai Yin (Author), Guojun Zhao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background:Astragalus mongholicus polysaccharides (APS) have anti-inflammatory, antioxidant and immunomodulatory effects. Recent studies have demonstrated the epigenetic regulation of N6-methyladenosine (m6A) in the development of inflammation. However, the effect of APS on m6A modification is uncle...