Wnt/β-catenin signalling in ovarian cancer: Insights into its hyperactivation and function in tumorigenesis

• Κύριοι συγγραφείς: Vu Hong Loan Nguyen (Συγγραφέας), Rebecca Hough (Συγγραφέας), Stefanie Bernaudo (Συγγραφέας), Chun Peng (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: BMC, 2019-12-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Abstract Epithelial ovarian cancer (EOC) is the deadliest female malignancy. The Wnt/β-catenin pathway plays critical roles in regulating embryonic development and physiological processes. This pathway is tightly regulated to ensure its proper activity. In the absence of Wnt ligands, β-catenin is de...