Interactions among ryanodine receptor isotypes contribute to muscle fiber type development and function

• Prif Awduron: Alexis A. Chagovetz (Awdur), Dana Klatt Shaw (Awdur), Erin Ritchie (Awdur), Kazuyuki Hoshijima (Awdur), David J. Grunwald (Awdur), Annemieke Aartsma-Rus (Awdur), James Dowling (Awdur), Maaike van Putten (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: The Company of Biologists, 2020-02-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Mutations affecting ryanodine receptor (RyR) calcium release channels commonly underlie congenital myopathies. Although these channels are known principally for their essential roles in muscle contractility, mutations in the human RYR1 gene result in a broad spectrum of phenotypes, including muscle...