Receptor-binding domain of MERS-CoV with optimal immunogen dosage and immunization interval protects human transgenic mice from MERS-CoV infection

• Main Authors: Yufei Wang (Author), Wanbo Tai (Author), Jie Yang (Author), Guangyu Zhao (Author), Shihui Sun (Author), Chien-Te K. Tseng (Author), Shibo Jiang (Author), Yusen Zhou (Author), Lanying Du (Author), Jimin Gao (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Middle East respiratory syndrome (MERS) continues to raise worldwide concerns due to its pandemic potential. Increased MERS cases and no licensed MERS vaccines highlight the need to develop safe and effective vaccines against MERS. We have previously demonstrated that a receptor-binding domain (RBD)...