Inhibition of osteoblast activity by zoledronic acid

• Main Authors: Fernanda Gonçalves Basso (Author), Ana Paula Silveira Turrioni (Author), Josimeri Hebling (Author), Carlos Alberto de Souza Costa (Author)
• Format: Book
• Published: Sociedade Brasileira de Patologia Clínica, 2013-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

INTRODUCTION: Patients treated with nitrogen-containing bisphosphonates, such as zoledronic acid (ZA), have frequently shown oral bone exposure areas, termed osteonecrosis. In addition, these patients may also present low repair and regeneration potential, mainly after tooth extractions. These side-...