Cell-Based Radiotracer Binding and Uptake Inhibition Assays: A Comparison of In Vitro Methods to Assess the Potency of Drugs That Target Monoamine Transporters

• Main Authors: Marija Ilic (Author), Marion Holy (Author), Kathrin Jaentsch (Author), Matthias E. Liechti (Author), Gert Lubec (Author), Michael H. Baumann (Author), Harald H. Sitte (Author), Dino Luethi (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

High-affinity monoamine transporters are targets for prescribed medications and stimulant drugs of abuse. Therefore, assessing monoamine transporter activity for candidate medications and newly-emerging drugs of abuse provides essential information for industry, academia, and public health. Radiotra...