Involvement of Parkin‐mediated mitophagy in the pathogenesis of chronic obstructive pulmonary disease‐related sarcopenia

• Main Authors: Akihiko Ito (Author), Mitsuo Hashimoto (Author), Jun Tanihata (Author), Sachi Matsubayashi (Author), Ryoko Sasaki (Author), Shota Fujimoto (Author), Hironori Kawamoto (Author), Yusuke Hosaka (Author), Akihiro Ichikawa (Author), Tsukasa Kadota (Author), Yu Fujita (Author), Daisuke Takekoshi (Author), Sabro Ito (Author), Shunsuke Minagawa (Author), Takanori Numata (Author), Hiromichi Hara (Author), Tatsuki Matsuoka (Author), Jun Udaka (Author), Jun Araya (Author), Mitsuru Saito (Author), Kazuyoshi Kuwano (Author)
• Format: Book
• Published: Wiley, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Sarcopenia is characterized by the loss of skeletal muscle mass and strength and is associated with poor prognosis in patients with chronic obstructive pulmonary disease (COPD). Cigarette smoke (CS) exposure, a major cause for COPD, induces mitochondrial damage, which has been im...