Pharmacological treatment and BBB-targeted genetic therapy for MCT8-dependent hypomyelination in zebrafish

Hypomyelination is a key symptom of Allan-Herndon-Dudley syndrome (AHDS), a psychomotor retardation associated with mutations in the thyroid-hormone (TH) transporter MCT8 (monocarboxylate transporter 8). AHDS is characterized by severe intellectual deficiency, neuromuscular impairment and brain hypo...

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Main Authors: David Zada (Author), Adi Tovin (Author), Tali Lerer-Goldshtein (Author), Lior Appelbaum (Author)
Format: Book
Published: The Company of Biologists, 2016-11-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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