Sulfonated Amphiphilic Poly(α)glutamate Amine-A Potential siRNA Nanocarrier for the Treatment of Both Chemo-Sensitive and Chemo-Resistant Glioblastoma Tumors

Sulfonated Amphiphilic Poly(α)glutamate Amine-A Potential siRNA Nanocarrier for the Treatment of Both Chemo-Sensitive and Chemo-Resistant Glioblastoma Tumors

Development of chemo-resistance is a major challenge in glioblastoma (GB) treatment. This phenomenon is often driven by increased activation of genes associated with DNA repair, such as the alkyl-removing enzyme O<sup>6</sup>-methylguanine-DNA methyltransferase (MGMT) in combination with...

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Main Authors: Adva Krivitsky (Author), Sabina Pozzi (Author), Eilam Yeini (Author), Sahar Israeli Dangoor (Author), Tal Zur (Author), Sapir Golan (Author), Vadim Krivitsky (Author), Nitzan Albeck (Author), Evgeny Pisarevsky (Author), Paula Ofek (Author), Asaf Madi (Author), Ronit Satchi-Fainaro (Author)
Format: Book
Published: MDPI AG, 2021-12-01T00:00:00Z.
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3rd Floor Main Library

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