TNF Superfamily: A Growing Saga of Kidney Injury Modulators

• Main Authors: Maria D. Sanchez-Niño (Author), Alberto Benito-Martin (Author), Sara Gonçalves (Author), Ana B. Sanz (Author), Alvaro C. Ucero (Author), Maria C. Izquierdo (Author), Adrian M. Ramos (Author), Sergio Berzal (Author), Rafael Selgas (Author), Marta Ruiz-Ortega (Author), Jesus Egido (Author), Alberto Ortiz (Author)
• Format: Book
• Published: Hindawi Limited, 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Members of the TNF superfamily participate in kidney disease. Tumor necrosis factor (TNF) and Fas ligand regulate renal cell survival and inflammation, and therapeutic targeting improves the outcome of experimental renal injury. TNF-related apoptosis-inducing ligand (TRAIL and its potential decoy re...