Reduced somatostatin signalling leads to hypersecretion of glucagon in mice fed a high-fat diet
Objectives: Elevated plasma glucagon is an early symptom of diabetes, occurring in subjects with impaired glucose regulation. Here, we explored alpha-cell function in female mice fed a high-fat diet (HFD). Methods: Female mice expressing the Ca2+ indicator GCaMP3 specifically in alpha-cells were fed...
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| Main Authors: | , , , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2020-10-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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