Excess of leptin inhibits hypothalamic expression in pubertal mice

• Main Authors: Sung Yeon Ahn (Author), Sei Won Yang (Author), Hee Jae Lee (Author), Jong Seon Byun (Author), Ji Yeon Om (Author), Choong Ho Shin (Author)
• Format: Book
• Published: Korean Pediatric Society, 2012-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

PurposeLeptin has been considered a link between metabolic state and reproductive activity. Defective reproductive function can occur in leptin-deficient and leptin-excessive conditions. The aim of this study was to examine the effects of centrally injected leptin on the hypothalamic KiSS-1 system i...