Pharmacokinetic analysis of linezolid for multidrug resistant tuberculosis at a tertiary care centre in Mumbai, India

• Main Authors: Juan Eduardo Resendiz-Galvan (Author), Prerna R. Arora (Author), Mahmoud Tareq Abdelwahab (Author), Zarir F. Udwadia (Author), Camilla Rodrigues (Author), Amita Gupta (Author), Paolo Denti (Author), Tester F. Ashavaid (Author), Jeffrey A. Tornheim (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Linezolid is an oxazolidinone used to treat multidrug-resistant tuberculosis (MDR-TB), including in the recently-endorsed shorter 6-month treatment regimens. Due to its narrow therapeutic index, linezolid is often either dose-adjusted or discontinued due to intolerance or toxicity during treatment,...