Human-likeness of antibody biologics determined by back-translation and comparison with large antibody variable gene repertoires

The antibody (Ab) germline gene rearrangement of variable (V), diversity (D), and joining (J) gene segments, as well as somatic hypermutation, give rise to the human Ab variable gene sequence repertoire. It is common to characterize single nucleotide frequencies of the variable region by alignment t...

Full description

Saved in:
Bibliographic Details
Main Authors: Samuel Schmitz (Author), Cinque Soto (Author), James E. Crowe (Author), Jens Meiler (Author)
Format: Book
Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
Subjects:
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

Connect to this object online.

3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available