Iso-α-Acids, Bitter Components in Beer, Suppress Inflammatory Responses and Attenuate Neural Hyperactivation in the Hippocampus

• Main Authors: Yasuhisa Ano (Author), Misato Yoshikawa (Author), Yuta Takaichi (Author), Makoto Michikawa (Author), Kazuyuki Uchida (Author), Hiroyuki Nakayama (Author), Akihiko Takashima (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Due to the growth in aging populations worldwide, prevention and therapy for age-related cognitive decline and dementia are in great demand. We previously demonstrated that long-term intake of iso-α-acids, which are hop-derived bitter compounds found in beer, prevent Alzheimer's pathology in a...